Reagent Grade Sodium Acetate Anhydrous

Reagent Grade Sodium Acetate Anhydrous – High Purity Laboratory Chemical for Analytical & Research Applications

Shanxi Zhaoyi Chemical Co., Ltd. makes laboratory chemical reagents. That is the one thing we do. Acetate has been coming out of our plant since 1988. Over 35 years in the trade by now. Our production facility follows one standard, and it covers 27,000 ㎡. Each year 150,000 tons leave the line, a number that holds steady. Labs and research institutes worldwide get raw material support from us that never wobbles. Purity starts at 99%. We built Reagent Grade Sodium Acetate Anhydrous for analytical chemistry and tough lab work. No water sits in the formula. Molecular weight: 82.03 g/mol. The CAS number is 127-09-3. Moisture, then, has no way to interfere. Stoichiometric math holds exact in buffer preparation and biochemical studies. Authorities in several countries issue our ISO, KOSHER and HALAL certificates. Impurity levels stay low. Moisture sits at ≤0.5%. For heavy metal the cap is ≤0.0005%. Chloride tops out at ≤0.005%. Reagent this pure is what molecular biology testing relies on. Lab instrument calibration does too. The powder is white and crystalline. Water dissolves it easily. Alkalinity stays mild.

Key Features & Benefits

Production and testing for this product follow laboratory-grade standards. That is how common headaches in research labs get fixed. Dirty reagents cause errors. Data from experiments drifts. Numbers in calculations come out wrong.

Ultra-High Purity, Zero Experimental Interference: Purity holds at ≥99%. Heavy metal content stays strictly under 0.0005%. Chloride content sits under 0.005%. Trace analysis and silver-related assays face no impurity in the way. Data stays accurate, and it repeats.

Stable Anhydrous Formula, Accurate Dosing Calculation: Water sits at ≤0.5%, and it stays there. Nothing shifts it. With trihydrate sodium acetate, crystal water pulls a 40% weight error into the mix. Not here. The molar concentration you worked out holds steady in your buffer solution, so no drift shows up. Run any pH-sensitive test that calls for precision, and this reagent handles it.

Quick Dissolution & Long-Term Stability: The crystal structure comes out fine and even. In water it breaks apart fast, and nothing is left behind. Keep the reagent dry, the way most people do. Chemical properties then last up to 24 months. Fewer raw materials end up in the bin. Your money stays put too, since spoiled reagent no longer means repeat runs.

Broad Compatibility & Robust Versatility: Work in analytical chemistry and biochemical research calls for a lot of different things. This reagent covers them. Labs stir it into HPLC mobile phase buffers. Genomic DNA and RNA precipitation are jobs it handles too. Cell culture media is another common use, and enzyme activity detection is one more.

Technical Specifications

How It Works

Reagent Grade Sodium Acetate Anhydrous keeps pH steady. It also lends a hand in nucleic acid purification, and it changes ionic strength in solutions. Why does that happen? The compound splits into ions, which balances chemical reactions. Tests that demand very accurate results count on this.

Stable Buffer System Mechanism: When you put it in water, it comes apart fully. Sodium ions and acetate ions are released. Together with acetic acid, these ions make a classic buffer system. Its pKa is 4.76. Acetate ions neutralize any added acid or alkali. The pH stays steady. It also works well in many precision tests that depend on pH.

Efficient Nucleic Acid Precipitation & Purification: In molecular biology, acetate ions at high concentration make DNA and RNA less able to dissolve in water. Add alcohol solutions to them, and nucleic acids fall out fast. Then centrifugation pulls them apart. Protein activity stays intact. The sample comes out purer.

Ionic Strength Optimization: The ionic strength of a test solution can be set with high precision. Enzyme proteins hold their spatial conformation steady. Chromatographic separation also gives much better resolution. For protein purification and chromatographic analysis, nothing else does the job.

Applications

Analytical Chemistry Labs: Standard acetate buffer solutions get made all the time in these labs. Colorimetric detection depends on them. So does titration analysis. Spectrophotometry is another method that needs them. A steady pH keeps the data accurate. That matters a lot when calcium, magnesium, and other metal ions are measured.

Biochemical Research: In molecular biology, this reagent gets used all the time for DNA/RNA extraction. Purification relies on it. Salt levels in the solution stay under control. The pH stays stable too. Nucleic acid samples then come back with high recovery rates. Enzyme activity also holds steady through biochemical experiments.

Quality Control Testing: This standard has high purity. Labs use it every day to calibrate pH meters. Conductivity meters get calibrated with it as well. Other analytical instruments get tested against it too. It matches the reference material prep standards that ISO-certified testing labs follow.

Educational Institutions: University chemistry and biology teaching labs put it to good use. Students mix buffer solutions with it. How acid-base balance works, it also helps show. Basic biochemistry experiments can run with it as well. Safe to handle. Results repeat well from one run to the next.

Reagent Grade Sodium Acetate Anhydrous vs Other Products

Certifications & Compliance

Our production system strictly abides by ISO 9001 international quality management system standards, realizing full-process standardized control from raw material input to finished product delivery and ensuring consistent batch stability of reagents. This product fully meets international laboratory reagent grade specifications and has obtained KOSHER and HALAL certifications, adapting to the use requirements of laboratories with special compliance standards.

Every batch of products is accompanied by a complete Certificate of Analysis (CoA), with detailed test data of all indicators, providing full compliance certification and quality traceability support for customer experimental research and laboratory qualification filing.

Packaging Options

We provide professional laboratory-grade classified packaging solutions, all with excellent moisture-proof and sealing performance to avoid reagent moisture absorption and contamination, ensuring long-term stable storage and use of reagents:

Laboratory-Scale Packaging: HDPE bottles come in 500g or 1kg sizes. Each one has an induction sealing cap. Air and moisture cannot get in. For small daily lab batches, that is handy. You can open them and use them again and again.

Bulk Research Quantities: Bags are sold in 5kg and 25kg sizes. Each one is a multi-layer composite. Inside sits aluminum foil, which acts as the barrier layer. Kraft paper wraps the outside for protection. Water vapor gets through very slowly. At large research institutes, work runs for years, so they buy these sizes.

Custom Configurations: Institutional customers can get personalized packaging from us. That includes reagent split packaging and custom labels. Special storage and distribution needs are covered this way. For a custom solution, get in touch with our team.

Manufacturing Process

High-Purity Raw Material Screening: Sodium hydroxide and reagent-grade, high-purity acetic acid come from approved vendors. For every incoming batch, we run spectral analysis. Any material that fails the bar gets removed. This step also guarantees that no impurities enter at the source.

Precision Controlled Synthesis: The neutralization reaction runs inside a constant-temperature jacketed reactor. We hold the temperature at ±2°C. Online pH checks happen in real time throughout the run. No excess alkali is left behind, because the reaction stays complete. This step also forms the base for final products of high purity.

Vacuum crystallization and dehydration rely on low-temperature vacuum evaporation. Heat can break down active substances, so this method stops that. The result is anhydrous crystal powder that meets spec. Moisture left in it is very low. Three steps get us there. Graded cooling crystallization comes first. Next is centrifugal separation. Low-humidity multi-stage drying finishes the job.

Strict Batch Testing: Every finished batch goes through a full-index test with 15 items. Karl Fischer moisture testing is one part of it, along with ion chromatography anion analysis and ICP-MS trace metal identification. Packing and shipping only happen once a product meets the reagent-grade requirements.

Why Choose Us

35+ Years of Professional Acetate R&D and Production: Acetate series products have been our focus since 1988. Our reagent-grade production processes for Reagent Grade Sodium Acetate Anhydrous are mature, and we know this industry inside out. That is why product quality stays dependable.

Stable Global Supply Capacity: Each year we turn out 150,000 tons. Stock points sit in many parts of the world, and that shortens delivery times. Raw material markets rise and fall. Even then, buyers keep getting a steady supply.

Professional Technical After-Sales Support: A team of chemists stands behind every order. From start to finish, they handle the technical side. Buffer formulas need tuning, or an experiment plan runs into trouble, and they take care of that too. If lab research hits a snag, customers can ask them for help.

Complete Traceability System: Every batch comes with its full production details. Batch records ship along with it, plus data on how long the product stays valid. Labs and research projects can then meet their audit traceability rules.

FAQ

Q: What is the way to turn sodium acetate trihydrate into the anhydrous form?

A: A1: The 0.6× factor takes care of the swap. By weight, sodium acetate trihydrate holds about 40% crystal water. So 0.6 parts of the anhydrous form replace 1 part of the trihydrate. Go back and check the buffer molarity too, so your experiment stays accurate.

Q: Why does the reagent start to clump after the container is opened?

A: A2: Moisture in the air gets pulled in by this anhydrous reagent with no trouble at all. Caking happens for that reason. The moment you stop using it, close the container. Put a silica gel desiccant in the dryer, and the powder keeps flowing freely.

Q: What pH does a 5% aqueous solution have?

A: A3: A 5% solution in water sits at a pH of 7.5 to 9.0. It stays in that range. That tells you the solution is weakly alkaline. To get an exact acidic buffer, though, you have to mix it with acetic acid. The amounts come from the Henderson-Hasselbalch formula.

Q: Can it be used to prepare HPLC mobile phase?

A: A4: Yes. The product has very low levels of chloride and heavy metals. Because of that, it won't pollute the chromatographic column. It also won't disturb the baseline. Use HPLC-grade water for dissolution. Detection performance stays stable this way.

Q: How do we get rid of reagents that were not used?

A: A5: Using small amounts is safe. No toxic risk there. The product also breaks down in nature on its own. Need to dump a larger amount? Balance that waste with a weak acid first. Keep at it until the pH reads between 6 and 8. Then dispose of it under your local environmental rules. Advice from the lab's chemical waste handlers is another option.

Request a Quote

Feel free to contact our professional sales team for exclusive Reagent Grade Sodium Acetate Anhydrous quotations and sample support: sxzy@sxzhaoyi.com