Laboratory Grade Sodium Acetate Anhydrous
CAS NO.: 127-09-3
Molecular Formula: CH₃COONa
Molecular Weight: 82.03 g/mol
Character: White crystalline powder or granules. It is readily soluble in water, slightly soluble in alcohol, and hygroscopic. Its aqueous solution is mildly alkaline.
Grade: Laboratory Grade
Usage: Mainly used for preparing buffer solutions, adjusting pH, analytical chemistry, biochemical experiments, chemical synthesis, molecular biology research, laboratory teaching, and other scientific research applications.
Package: 500 g, 1 kg, 5 kg, 25 kg, or customized laboratory-grade packaging.
Storage: Store in a tightly closed container in a cool, dry, and well-ventilated place. Protect from moisture, contamination, strong acids, strong oxidizing agents, and package damage.
- Product Description
Laboratory Grade Sodium Acetate Anhydrous | High Purity Chemical Reagent for Analytical Research
Shanxi Zhaoyi Chemical Co., Ltd. makes laboratory chemical reagents. Precision holds at every step. Our factory covers 27,000 ㎡ and works off one standard setup. Behind us sit more than 35 years of production experience. Each year the plant turns out 150,000 tons of acetate series products. From that output, labs and scientific research institutions worldwide get a steady supply of raw material. Our Laboratory Grade Sodium Acetate Anhydrous (CAS 127-09-3) is a white crystalline reagent. It meets a high standard. Purity sits at 99% or above. Water can throw off a precision experiment, so manufacturing follows a strict anhydrous formula to keep it out. Heavy metal content stays under 0.0005%. Chloride impurity stays under 0.005%. Everywhere lab reagent standards apply, this product meets them. Buyers in Europe, America, and Asia use it for high-precision analytical research. ISO approval is in place. National authorities have also granted KOSHER and HALAL certifications.

Key Features & Benefits
Biochemical research and high-precision analytical tests are what this product was built for. Raw materials of the common kind bring their own set of problems. Experiment data turns unstable. Reagents go bad fast. Our product fixes both of those problems.
Quick Dissolution & Stable Solution Performance: Put the homogeneous crystalline powder in water. It breaks down completely, and fast. What you get is a stable solution with a mild alkaline character. From there, pH can be tuned in a careful and controlled way. Nothing else goes in. That means no extra impurity factors show up. Experiments stay repeatable and precise as a result.
Strict Anhydrous & Anti-Deterioration: Moisture wrecks some tests. For those, the answer is the anhydrous production process. Crystal water gets pulled out of the product. Reagents then stop failing from moisture uptake. Less lab raw material goes to waste. Sealed storage keeps things stable for a long time.
Ultra-Low Impurity & High Consistency: A tiny pollutant can change what an experiment shows. Purification goes through many stages, and strict batch tests clear every one of them out. That makes long-term studies possible for research staff. Because the indications stay steady from one batch to the next, many groups can compare their results.

Technical Specifications
Parameter | Specification |
|---|---|
Chemical Formula | CH₃COONa |
Molecular Weight | 82.03 g/mol |
CAS Number | 127-09-3 |
Appearance | White crystalline powder/granules |
Purity (CH₃COONa) | ≥99.0% |
Water Content | ≤0.5% |
Chloride (Cl) | ≤0.005% |
Heavy Metals (as Pb) | ≤0.0005% |
Iron (Fe) | ≤0.0003% |
pH (5% aqueous solution) | 7.5–9.0 |
Solubility | Freely soluble in water, slightly soluble in alcohol |

How It Works
The product holds pH buffering at a steady level. It also lends a hand to nucleic acid precipitation and catalytic reactions. Ionic dissociation and chemical equilibrium are what drive those effects. Plenty of precision lab experiments rely on those roles.
Stable Acetate Buffer System: Put this product in water. It breaks apart all the way, into sodium ions and acetate ions. Then add acetic acid. You get a classic acid-base buffer. The acetate ions soak up extra protons. They also neutralize unwanted alkalis. The pH of the solution holds between 3.6 and 5.6. pH shifts can ruin experiments. This buffer stops that kind of mistake.
Effective Nucleic Acid Precipitation: In molecular biology, sodium cations remove the negative charge found on the surface of DNA and RNA phosphate backbones. Genetic materials no longer push each other away through electrostatic repulsion. In alcohol solutions, nucleic acids then form a precipitate with much less trouble. After that, you can extract a high-purity sample.
Mild Catalytic Reaction Assistance: This reagent is only mildly alkaline. It gives organic synthesis steps, such as acetylation and esterification, a steady weak-base environment. Reactions go faster. Side reactions are blocked too. Raw materials are less likely to break down. Strong acid and strong base catalysts often cause those problems.
Applications
Analytical Chemistry Laboratories: Labs often reach for this one when they make standard buffer solutions. pH calibration reagents are another regular use. So are chromatographic mobile phases. At this purity level, the baseline stays flat. Spectral analysis readings turn out correct. Titration results hold up just as well.
Biochemical Research: Pulling out and precipitating DNA and RNA calls for this reagent. It plays a main part there. During enzymatic reactions, the pH stays in the right range. Protein activity does not drop off either. Tough biochemical tests and sample work need exactly that.
Chemical Synthesis: Mild base catalyst is one role it plays. Acetate ions also come out of it. Esterification is one reaction that uses it, acetylation is another. The same holds for other organic modification work. Control over conditions gets easier. Finished product comes out purer.
Molecular Biology Workstations: While gel electrophoresis separation runs, the system pH stays put. Protein dialysis fits here too. Purification work belongs in this group as well. Results in molecular biology hold steady. Each repeat gives the same outcome.
Educational Institutions: Chemistry classes at universities and research institutes put it to use. Research experiments there fit it too. Buffer solution ideas become something students can see in a practical setting. Organic reaction mechanisms get demonstrated in that same hands-on way. Everyday teaching tasks and research tasks are both covered.
Product Comparison
Feature | Laboratory Grade Sodium Acetate Anhydrous | Sodium Acetate Trihydrate | Sodium Bicarbonate |
|---|---|---|---|
Water Content | ≤0.5% | ~40% (crystal water) | N/A |
Molecular Weight | 82.03 g/mol | 136.08 g/mol | 84.01 g/mol |
Hygroscopicity | High (requires sealed storage) | Lower (stable hydrate) | Moderate |
Buffer pH Range | 3.6–5.6 (with acetic acid) | 3.6–5.6 (with acetic acid) | 9.0–10.5 |
Concentration Accuracy | Higher (no water dilution) | Requires conversion calculation | Different buffering mechanism |
Shelf Stability | Excellent when sealed | Good | May release CO₂ over time |
Typical Use Cases | Water-sensitive reactions, precise molarity | General buffering, less critical applications | Alkaline buffering only |
Certifications & Compliance
No corners get cut in our production system, which follows international quality management standards. ISO 9001:2015 quality system certification is something we hold. KOSHER and HALAL certificates come with every laboratory-grade reagent. Those same standards are what researchers and industry teams worldwide work to.
EU REACH and US TSCA chemical safety rules are met by every product. A full Certificate of Analysis (CoA) ships with each batch. Production indicators can be traced from start to finish. Global customers can then wrap up lab qualification checks and project filing fast.

Laboratory Grade Sodium Acetate Anhydrous Packaging Options
Labs run at different scales and use reagents at different rates. So we offer packaging in several grades. All of it uses a professional moisture-proof and pollution-proof design. Product activity and purity stay intact:
500g Bottles: Precision tests on a small scale suit these well. A lab that reaches for the reagent only now and then gets good use out of them too. When fewer Laboratory Grade Sodium Acetate Anhydrous containers sit open, moisture has a harder time creeping in.
1kg Bottles: The most cost-effective option for conventional laboratory daily testing and medium-frequency experimental research.
5kg Containers: Ideal for research institutions with long-term routine buffer solution preparation and large-volume experimental projects.
25kg Drums: Large laboratories order in bulk. Scientific research bases do the same, along with industrial research and development departments. They need this size to keep up with high-volume usage.
Custom Packaging: Tell us how you store the material. What your tests do with it matters too. Packaging gets designed around those answers.
Inside every package there is an airtight seal, plus a liner that stops moisture. Outside moisture and pollutants cannot get past them. The product also holds up well in shipping and storage.

Manufacturing Process
Our raw materials are certified acetic acid and sodium hydroxide. Both come at high purity. That way nothing unwanted gets in at the start. A closed reactor handles the neutralization step, and the temperature stays constant. Real time checks cover pH and reaction progress, all under tight control.
The reaction finishes, and after that the solution passes through a few crystallization stages. Each stage runs at its own gradient. This is where soluble impurities drop out. Next comes centrifugal separation. Drying happens under vacuum, at low temperature. That step pulls out all the crystal water, so heat never breaks the active ingredients down. The anhydrous specs then end up inside the required limits.
Milling comes last. Particle size drops to one steady level here. After that, a full-index quality check runs. Packing is done in a workshop with no dust and no contamination. Every batch gets tested for purity, moisture content and heavy metals. Nothing leaves until it passes. The batch qualification rate holds at 100%.
Why Choose Us
Decades of Expert Acetate Manufacturing: Since our founding in 1988, we have concentrated on the development and manufacturing of acetate reagents for over 35 years. We have advanced process technology and extensive knowledge in customizing laboratory reagents.
Stable Large-Scale Supply: Long-term stable collaboration with scientific research institutions is supported by a 150,000-ton yearly manufacturing capacity and adequate inventory reserves that totally prevent out-of-stock and delayed delivery.
Strict Quality Control System: Every batch of reagent has to perform the same way. That is why we keep an eye on the whole process, from the raw materials coming in to the finished product going out. An independent lab and a trained inspection crew are part of that setup.
Global One-Stop Service: Customs paperwork gets handled for you. Support from our technical team after you buy comes with the package too. Both depend on a cross-border logistics network we have built over the years. Europe, America, Asia, and other regions all fall inside that reach.
Expert Technical Support: Client research does not always go to plan. Our technical staff can advise on an experimental formula. They will also tell you how much reagent to use. Trouble shows up sometimes. Sorting it out is part of what they do.

FAQ
Q: To swap out one part of the trihydrate form, what amount of anhydrous sodium acetate do you need?
A: A1: Roughly 40% of the trihydrate form is crystal water. In lab work, 0.6 parts of the anhydrous product can take the place of 1 part of the trihydrate. Look at the molarity of your buffer solution one more time after that. That keeps your experiment accurate.
Q: Why does the reagent clump after you open it?
A: A2: Moisture gets pulled in by this product very fast. If it sits in damp air, water goes into it. Lumps start to form. Once you are done using it, close the container right away. Store it somewhere dry. The relative humidity in that spot needs to stay under 65%.
Q: Could I use this product to bring the pH of a solution down?
A: A3: No. Mix our anhydrous sodium acetate with water and it becomes a mildly alkaline solution. It only holds pH steady and adjusts alkalinity. To bring the pH value down, use it with acetic acid.
Q: How long does the product keep?
A: A4: Keep the product sealed and dry and an unopened pack lasts 12 months. Once opened, use it within 48 hours. If that is not possible, store it in an airtight container with a desiccant.
Q: Will it produce peculiar smell or affect experimental results?
A: A5: In normal lab work, you use 0.1%-0.5%. At that level it gives off almost no smell. The reaction is not affected either. If you smell something odd or taste metal, the batch is contaminated. Stop using it at once.

Request a Quote
Feel free to contact our professional sales team for exclusive quotations and technical support for Laboratory Grade Sodium Acetate Anhydrous: sxzy@sxzhaoyi.com


