5M Potassium Acetate Solution

5M Potassium Acetate Solution | Laboratory-Grade Molecular Biology Buffer | High-Purity Ready-to-Use Research Chemical

Acetate reagents have been coming out of Shanxi Zhaoyi Chemical Co., Ltd. since 1988. That works out to over 35 years. Our plant covers 27,000 m², and 150,000 tons of acetate leave it every year. Labs and research sites around the world buy our laboratory-grade biochemical reagents. The 5M Potassium Acetate Solution (CAS NO. 127-08-2, CH3COOK, Molecular Weight: 98.14) is a concentrated stock solution. It is clear and has no color. Molecular biology and biochemical research are what we make it for. Used as a buffer reagent, it needs no prep at all. Molarity stays exact. Purity runs high. Each batch acts the same as the one before it. Lab prep gets lighter, and your results hold up when you run them again.

Key Features & Benefits

Nucleic acid precipitation and biochemical buffer prep are the two jobs our this product is made for. Daily lab work throws up a few headaches when you mix your own reagents, and this one takes care of them:

Precise & Stable Molarity: The factory sets the concentration. Nothing has to be weighed, diluted, or calibrated. That wipes out the errors people make with their own mixes. Core molecular biology experiments run faster this way, and the data repeats better.

High Optical Clarity: No color shows up in this liquid. It is clear, and nothing solid floats in it. That is what makes it work for so many spectrophotometric tests. Mix a buffer on your own and tiny bits of dirt tend to sneak in. Those particles throw the readings off, so the data comes back wrong. Here, that problem does not exist.

Long-Term pH Stability: A professional stabilization process holds the pH steady for the entire storage period. Ordinary reagents wander. A run then falls apart and the test has to be done again. Neither of those things happens with this buffer. Lab work keeps moving, with fewer stops.

High Compatibility for Biochemical Experiments: Production is governed by strict molecular biology-grade purity standards. Enzymes do not lose speed in this solution. Biochemical reactions are not disturbed either. So precision work, such as molecular cloning and DNA extraction, succeeds more often.

Technical Specifications

How It Works

This product works through mild buffering and ionic interaction. Plenty of molecular biology and biochemical experiments get steady, focused support from this product:

Nucleic Acid Stabilization & Precipitation: A potassium cation carries a positive charge. That charge latches onto the negatively charged backbone of nucleic acids. The molecule is held steady this way. Samples then settle out fully during precipitation work. Structure stays intact in the nucleic acid.

Selective Impurity Removal: In plasmid DNA isolation protocols, this solution neutralizes alkaline lysis buffer systems. Chromosomal DNA and protein impurity complexes fall out of the mix. Pure plasmid DNA stays in solution. Little effort is needed to get a purified sample.

A pH Buffer That Stays Put: Acetate anions form a buffer system. The pH range runs from 3.8 to 5.8. The reaction environment holds steady through enzymatic digestion and gene ligation. Other biochemical reactions keep a stable setting as well. So pH swings never turn into test errors.

Ionic Strength Set Just Right: The 5M formula is highly concentrated. This gives experimental systems a standard ionic strength. It breaks protein-DNA binding interactions, which denatures the protein. Nucleic acid samples stay undamaged.

Applications

This buffer solution is molecular biology grade. Many core research settings in life science and analytical biochemistry fit it. Labs at universities reach for it a lot. Research institutes do the same. Biopharma R&D companies use it as well:

Molecular Biology Research: A solid pick for DNA and RNA precipitation, plasmid purification and genomic DNA extraction. The concentration stays exact. Your conditions then hold steady from one run to the next. Sample yields come out repeatable too.

Biochemical Buffer Preparation: Picture a standard stock solution, mixed at a high strength. When working buffers are needed, you just dilute it. Chromatography and electrophoresis are two everyday uses. Other analytical work fits too. One bottle lets labs build many different buffer recipes.

Protein Crystallization: People often choose it for protein screening and stabilization studies. In crystallization runs, it holds a steady ionic environment that you can control. That helps structural biology work where precision counts.

Cell Culture Media: Inside this product, the acetate works as a constant carbon source in certain cell culture systems. We supply it at high purity. Cell lines that are sensitive need careful culturing and regular upkeep. This is a pharmaceutical grade, so it meets those needs.

5M Potassium Acetate Solution vs Other Products

Certifications & Compliance

Our production workshop strictly implements the ISO quality management system, realizing full-process standardized quality control from raw material procurement to finished product delivery. All reagents including 5M Potassium Acetate Solution have passed KOSHER and HALAL authoritative certifications, meeting the usage standards of global diversified scientific research institutions. In addition, we adopt GMP-compliant production specifications to ensure stable pharmaceutical-grade product quality. Each batch is equipped with complete test documents and qualification certificates, providing reliable data support for customers' experimental verification and regulatory declaration work.

Packaging Options

Labs run experiments at different scales, and daily use changes from one to the next. So we make packaging for each of those needs. It keeps the product stable and simple to handle:

500mL Amber Bottles: These bottles block light and seal tight. Use them every day in the lab. Light and moisture can spoil a reagent, and this packaging stops that from happening.

1L Standard Containers: A good pick for mid-size standard experiments. Price and ease of handling stay in balance here. Labs that run the same work day after day can keep using them long term.

5L Bulk Packaging: Large volumes come at a lower cost. Labs doing high throughput work, or research run in batches, find it a good fit. What you pay for each unit goes down.

Custom Packaging: We build packaging to your order. Nitrogen-filled sealing is one option. Special container materials are another. Both suit high-precision work and sensitive lab protocols. On top of that, every package gets a tamper-proof anti-counterfeiting seal and a batch number of its own. That gives you full traceability.

Manufacturing Process

Only high-purity potassium hydroxide and glacial acetic acid go in as raw materials. Both come from certified suppliers. That keeps the source clean. The neutralization synthesis reaction runs inside a sealed stainless steel reactor. Temperature and pressure are watched the whole time. This gives the reaction enough time and holds it steady.

The finished solution passes through multi-stage precision filtration. That step takes out particulate impurities and makes the liquid optically clear. To check concentration, we use professionally calibrated analytical instruments. Molarity error is held strictly within ±0.05M.

Every product gets bottled and sealed in a dust-free clean workshop. Before that step, it goes through microbiological detection and impurity screening. Each batch carries its own batch number. Production and testing records are kept complete. Traceability then covers the whole lifecycle.

Why Choose Us

With 35 years of focused acetate product manufacturing experience, we have a deep understanding of the quality standards and application requirements of research-grade biochemical reagents. Supported by 150,000 tons of annual production capacity, we can stably supply orders of all sizes and completely avoid stock-out delays for large-scale research projects.

Our logistics network has been running for years. Europe, America, Asia and other regions are all covered. Full customs paperwork leaves with every shipment, and the packing follows one standard. So labs anywhere can count on their goods arriving, and delivery stays fast and dependable.

A technical team that knows the work sits behind every order. Support costs nothing. It covers the whole job, from adjusting your experimental protocol to setting pH the way you want it. Standard reagents are only one part of what we sell. Tell us what your research calls for, and we will find a match for it.

FAQ

Q: Can we get This product at a pH we choose?

A: A1: Yes. pH can be fully customized. Your protocol decides the setting we use. Two custom specs show up most often. DNA precipitation runs at pH 4.8. Protein-related research applications usually need pH 7.5.

Q: How long does your product keep?

A: A2: Keep the lid on and store the bottle under normal conditions. Sunlight and heat sources should stay away from it. The physical and chemical properties do not change. It keeps for up to 24 months.

Q: Will this reagent work for RNA isolation experiments?

A: A3: Yes. Our solution is made to molecular biology grade, so there is no RNase in it. RNA will not degrade because of it. It also works with all kinds of RNA precipitation and isolation protocols.

Q: Is an official CoA document supplied with every batch?

A: A4: Yes. A full Certificate of Analysis ships with every order. Purity test data is listed there too. Exact molarity and pH values appear in the same document. Production batch information also comes with it. All of that covers lab filing and quality verification.

Q: Once the product arrives, how should I store it?

A: A5: Let it stay at room temperature (15-25°C). A dry spot with airflow works best. Do not put it in the cold. Never freeze it. Freezing may damage the container. It may also make the solution precipitate.

Request a Quote

If you need high-purity, stable 5M Potassium Acetate Solution and biochemical research workflows, sxzy@sxzhaoyi.com.